Design of studies for medical research医学研究的学习设计 umd mobi chm 夸克云 免费 azw3 下载 pdf

The same careful rigour imposed on the design of phase III randomised controlled trials is not always applied to medical research in other areas such as trials conducted at earlier stages of drug development。

With the emphasis that is now placed on evidence-based medicine，such care and rigour will inevitably impact on these areas with increasing attention turned to the quality of design。

This title describes what principles can be used to structure research effectively allowing for the required degree of accuracy。

Written by two best selling authors，this book includes many examples from medical literature and will be of great value to all groups conducting studies at the interface of clinical and laboratory research。

Preface.

Chapter 1. What is Evidence

Chapter 2. Measurement， Forms and Questionnaires

Chapter 3. Principles of Study Size Calculation

Chapter 4. Randomisation

Chapter 5. Cross-sectional Longitudinal Studies

Chapter 6. Surveys, Cohort and Case-Control Studies

Chapter 7. Clinical Trails - General Issues

Chapter 8. Early Clinical Trials

Chapter 9. Phase III Trials

Chapter 10. Diagnosis

Chapter 11. Prognostic Factor Studies

References

Tables

Index

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书籍介绍

The same careful rigour imposed on the design of phase III randomised controlled trials is not always applied to medical research in other areas such as trials conducted at earlier stages of drug development. With the emphasis that is now placed on evidence--based medicine, such care and rigour will inevitably impact on these areas with increasing attention turned to the quality of design. This title describes what principles can be used to structure research effectively allowing for the required degree of accuracy. Written by two best selling authors, this book includes many examples from medical literature and will be of great value to all groups conducting studies at the interface of clinical and laboratory research.